![]() ![]() Recently, a meta-analysis concluded that women who were older at the onset of natural menopause (≥55 years) had a higher risk of hemorrhagic stroke (pooled relative risk, 2.24 ). 7– 9 In the past decade, an increasing number of epidemiological studies have investigated the relationship between age at menopause and (ischemic and hemorrhagic) stroke risk, with conflicting results. Some studies have reported that early menopause increases the risk of cardiovascular diseases, 6 which is generally ascribed to the postmenopausal decrease in endogenous estrogens. 2 Women have around 4% higher lifetime stroke risk than men, 3– 5 which might be attributable to female-specific risk factors like the age at menopause. ![]() 1 Over the past years, the lifetime stroke risk has increased significantly. ![]() Stroke is the second leading cause of death worldwide affecting 2.6 million women in 2016. ![]()
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